On May 12, 1814, Tennessee settler Isaac Stephens wrote to his uncle Henry Mackey in Virginia about the Battle of Horseshoe Bend in Alabama. In that battle on March 27, 1814, US Army and Tennessee militia troops under General Andrew Jackson defeated 1000 warriors from the Creek confederation, ending the Creek War of 1812–1814.
A graduate of Syracuse Medical College, Mary Walker served as a doctor during the American Civil War. In April 1864, Walker was captured by the Confederates in Tennessee. Following her release, President Lincoln summoned Walker to Washington, DC, to discuss her imprisonment.